Preliminary remark by Prof. Citak: “When I started working with Transcranial Pulse Stimulation as one of the first practicing physicians, I was very skeptical despite my wide range of experience with shock waves and said ‘but if T. P. S. brings only 2% of treatment success of the other shock wave therapies I use, then that is already progress’. My first patient was the following Mrs. B., as our families are close friends. Unfortunately, the treatment did not achieve as much with my dear friend as it did with many others. But, it must be said clearly, this also happens and we are all grateful that we were at least able to achieve that Mrs. B. is well enough within her naturally limited life that she does not have to go to a nursing home, but can continue to live at home with her loved ones. We are certain that this would not have been possible without Transcranial Pulse Stimulation.”
The prehistory: M. B. is a today 77-year-old lady, who lives with her spouse S. B. in the north of Germany. Life was and is, as we shall see in spite of everything, extremely good to her: she grows up carefree and free in a wealthy family and can develop freely. And at a young age, in 1969 while studying Oriental Studies, she meets the love of her life, S. Today the two have been married 51 years, they have three grown sons, all of whom are well-born, as the saying goes. “Yes, we really have a love of life,” husband S. B. says in conversation, “We’ve never quarreled in all these years, there’s never been a bad word between us.” A rarity. S. B. starts a company after his studies, he becomes an international entrepreneur, his wife M. B. stays at home and raises the boys. But she is not a homebody! She has chosen this division herself, she keeps her husband’s back, she is versatile and actively engaged, she speaks several languages. M. B. is cultured, eloquent, educated, soulful and well-read, she has a library of more than 5000 books, she is an interested and lively spirit. And life continued to be kind to the B. family: there were never any health problems or unhealthy lifestyle, nothing that could have caused M. B. to develop dementia later.
But around the beginning of 2020, the couple, the children and the social environment notice that M. B. is becoming increasingly forgetful. At first, this is attributed to her age; she is 75 years old at this point, and one’s mind can slow down a bit. But the forgetfulness became more and more pronounced, and M. B. really began to deteriorate. One goes to the doctor.
With M. B. it goes comparatively fast, until a diagnosis is in the room. Although no abnormalities are seen in the EEG (electroencephalography, an examination method in which the electrical activity of the cerebral cortex is measured via electrodes) and the subsequent MRI also remains inconclusive. The neurologist performs all available tests and nevertheless sees a clear case: M. B. suffers from a demential syndrome, most likely in the form of Alzheimer’s dementia (note: Alzheimer’s dementia is usually a demential mixed form and can never be diagnosed 100% during a person’s lifetime, but only “post-mortem”, i.e. after death).
Accordingly, at the beginning of 2021, M. B. receives, among other things, risperidone (an antipsychotic used primarily to treat schizophrenia and bipolar disorders, but also for dementia) and later memantine (a derivative of amantadine, it is used to treat moderate to severe forms of dementia of the Alzheimer type). However, M.B. does not tolerate either because of numerous side effects, nor do the drugs halt the progression of the disease. In a short time, M. B. withdraws, she hardly speaks, only her husband she always asks with interest: “What did you do today? How are you?”. Otherwise, M. B. now lives in an inward-looking world. The medication is phased out and finally discontinued. The family knows there is nothing they can do about this disease, they have to accept it. They hire a nurse who, together with husband S. B., looks after M. B., who has become a nursing case, for several hours a day. But the anxious question looms as her condition deteriorates so quickly: will she soon have to go into a nursing home?
Fortunately, the B. family is friends with Prof. Musa Citak in Hamburg. The experienced shock wave specialist and expert in regenerative medicine has heard about Transcranial Pulse Stimulation and quickly becomes involved with the new therapy option. Prof. Citak decides, “And if this TPS can achieve only 2% of what can be achieved with my shock wave therapies in other medical fields, let’s give it a try.” No sooner said than done, Prof. Citak orders his first device and after extensive training, M. B. becomes his very first patient.
In the summer of 2021, M. B. receives her first six treatments. Although M. B. does not experience “aha experiences” and great mental improvements as many other patients do, from here on M. B. remains in a status quo, the disease does not progress any further. In the fall of 2021 and in May 2022, M. B. will be treated again with Transcranial Pulse Stimulation.
TPS now accomplishes what medication was intended to do and failed to do: it achieves disease arrest for M. B. And furthermore: M. B. starts to read again. Books have always been a central part of her life; every day she reads for hours, engrossed in her books. “Of course, I don’t know what’s going on inside her, but she seems happy doing it,” says husband S. B. and continues: “We also watch old movies together, which she enjoys. We understand each other, we also talk to each other, although without as many words as before. Our days are filled, we go for walks together, we go to celebrations, friends also visit us, she recognizes each one , but she hardly speaks a word to them.”
Our conversation takes a turn: “What do you think would have happened without the therapy?” raises S. B.’s question. “According to the neurologist and others, my wife would probably be in a nursing home by now, because we would probably not have been able to care for her at home for a long time, even with all our will. Until the TPS, the course of the disease was extremely fast.”
We discuss this topic in detail, we talk about the burden of moving into a nursing home, what emotional pain this represents for all those affected and, of course, for most people it also means a financial drama: on average, a family has to pay € 2,179 per month privately for a nursing place in Germany! And that is still by far not everything.
“From this point of view, the TPS is also a treatment success for us,” says S. B. and continues: “We live with the disease, and unless a miracle happens or the next TPS brings such a breakthrough for my wife as it did for many others, it will probably at least save us from this step. We can be satisfied that I can continue to live at home with my wife. How many people don’t have that advantage?”